"Prohibition has failed; legalisation is the least bad solution. A HUNDRED years ago a group of foreign diplomats gathered in Shanghai for the first-ever international effort to ban trade in a narcotic drug." Thus begins the march 5th 2009 leader in the renowned publication THE ECONOMIST. (Also, don't hesitate to check the readers comments; I recomend sorting them by popularity - if you really want to get into it THE ECONOMIST has actualy been pro-legalisation for 20 years and you can find some really insigthful articles on the subject on their site.)

"By any sensible measure, this 100-year struggle has been illiberal, murderous and pointless. That is why The Economist continues to believe that the least bad policy is to legalise drugs." The War on Drugs has been a complete failure, Mexico is on the brink of becoming a truly failed state, Afghan jihadists are supported mainly by drugtrade and we use as much or more drugs as we did in the past. "This is not for want of effort. The United States alone spends some $40 billion each year on trying to eliminate the supply of drugs. It arrests 1.5m of its citizens each year for drug offences, locking up half a million of them [...] Indeed, far from reducing crime, prohibition has fostered gangsterism on a scale that the world has never seen before. According to the UN’s perhaps inflated estimate, the illegal drug industry is worth some $320 billion a year. In the West it makes criminals of otherwise law-abiding citizens (the current American president could easily have ended up in prison for his youthful experiments with “blow”)"
On a personal note: What I personally dislike the most about using illegal drugs for medicinal and recreational purposes is the need to relate to criminals. I hate dealing with them, I hate the usually non-communal way they spend their profits (they cant reinvest because their money are dirty god damn it!) - and to be truly honest most criminals have serious behavioural issues and leaving the perscribing and distrobution of psycofarma-like drugs to sosiopaths when we even wont let psycologists perscribe a valium is closer to a crime against mankind than any thinking beeing should be able to comfortably contemplate.
Also; leaving extacy and drugs like it to the professionals (like Pfizer, Bauer and the rest of "Big Pharma") would be nothing but a happiful drug revolution.